PUBLICATIONS
BATEMAN, NICHOLASGarcia Osuna E, Hua J, Bateman NW, Zhao T, Berget PB, Murphy RF.
Large-scale automated analysis of location patterns in randomly tagged 3T3
cells. Ann Biomed Eng. 2007 Jun;35(6):1081-7.
Frey MR, Clark JA, Bateman NW, Kazanietz MG, Black AR, Black JD. Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells.
Biochem Pharmacol. 2004 May 15;67(10):1873-86.
Bateman NW, Tan D, Pestell RG, Black JD, Black AR. Intestinal tumor
progression is associated with altered function of KLF5. J Biol Chem. 2004
Mar 26;279(13):12093-101.
CONRADS, THOMAS
Conrads, T. P., Hemann, C., and Hille, R. (1998) Formation of a Tyrosyl Radical in Xanthine Oxidase, Biochemistry 37, 7787-7791.
Conrads, T. P., Anderson, G. A., Veenstra, T. D., Pasa-Tolic, L., and Smith, R. D. (2000) The Use of Accurate Mass Tags in Proteome-wide Protein Identification, Anal. Chem. 72, 3349-3354.
Belov, M, Nikolaev, E. N., Anderson, G. A., Udseth, H. R., Conrads, T. P., Veenstra, T. D. Masselon, C. D., Gorshkov, M. V., and Smith, R. D. (2001) Design and Performance of an ESI Interface for Selective External Ion Accumulation Coupled to a Fourier-Transform Ion Cyclotron Mass Spectrometer, Anal. Chem. 73, 253-261.
Ellis, P., Conrads, T. P., Hille, R., and Kuhn, P. (2001) The Crystal Structure of Alcaligenes faecalis Arsenite Oxidase, Structure 9, 125-132.
Shen, Y., Zhao, R., Belov, M. E., Conrads, T. P., Anderson, G. A., Tang, K., Pasa-Tolic, L., Veenstra, T. D., Lipton, M. S., and Smith, R. D. (2001) Packed Capillary Reversed-Phase Liquid Chromatography with High Performance Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for Proteomics, Anal. Chem. 73, 1766-1775.
Conrads, T. P., Alving, K., Veenstra, T. D., Belov, M. E., Anderson, G. A., Anderson, D. J., Lipton, M. S., Pasa-Tolic, L., Udseth, H. R., Chrisler, W., Thrall, B. D., and Smith, R. D. (2001) Quantitative Analysis of Proteomes Using a Combination of Cysteine Affinity Tags and 15N-Metabolic Labeling, Anal. Chem. 73, 2132-2139.
Goshe, M. B., Conrads, T. P., Panisko, E. A., Angell, N. H., and Veenstra, T. D. (2001) Phosphopeptide Isotope-coded Affinity Tag (PhIAT) Approach for Isolating and Quantitating Phosphopeptides, Anal. Chem. 73, 2578-2586.
Smith, R. D., Pasa-Tolic, L., Lipton, M. S., Jensen, P. K., Anderson, G. A., Shen, Y., Conrads, T. P., Udseth H. R., Harkewicz, R., Belov, M. E., Masselon, C., and Veenstra, T. D. (2001) Rapid Quantitative Measurements of Proteomes by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, Electrophoresis 22, 1652-1668.
Li, L., Masselon, C. D., Anderson, G. A., Pasa-Tolic, L., Lee, S. W., Shen, Y., Zhao, R., Lipton, M. S., Conrads, T. P., Tolic, N., and Smith, R. D. (2001) High-Throughput Peptide Identification from Protein Digests Using Data-Dependent Multiplexed Tandem FTICR Mass Spectrometry Coupled with Capillary Liquid Chromatography, Anal. Chem. 73, 3312-3322.
Goshe, M. B., Veenstra, T. D., Panisko, E. A., Conrads, T. P., Angell, N. H., and Smith, R. D. (2002) Phosphopeptide Isotope-coded Affinity Tags: Application to Enrichment and Identification of Low Abundance Phosphoproteins, Anal. Chem. 74, 607-616.
Smith, R. D., Anderson, G. A., Lipton, M. S., Pasa-Tolic, L., Shen, Y., Conrads, T. P., Veenstra, T. D., Udseth, H. R. (2002) An Accurate Mass Tag Strategy for Quantitative and High-throughput Proteome Measurements, Proteomics 2, 513-523.
Borisov, O. V., Goshe, M. B., Conrads, T. P., Veenstra, T. D., Rakov, V. S., and Smith, R. D. (2002) Low Energy CID Fragmentation Analysis of Cysteinyl-modified Peptides, Anal. Chem. 74, 2284-2292.
Weirenga, S. K., Zocher, M. J., Mirus, M. M., Conrads, T. P., Goshe, M. B., and Veenstra, T. D. (2002) Evaluation of Tryptic Digest Conditions for High Throughput Proteome Analyses, Rap. Comm. Mass Spectrom. 16, 1404-1408.
Yu, L. R., Johnson, M. D., Conrads, T. P., Smith, R. D., Morrison, R. S., and Veenstra, T. D. (2002) Proteome Analysis of Camptothecin-treated Cortical Neurons using Isotope-coded Affinity Tags, Electrophoresis 23, 1591-1598.
Yu, L. R., Morrison, R. S., Johnson, M. D., Conrads, T. P. and Veenstra, T. D. (2002) Isotope-coded Affinity Tag Analysis of Native and Camptothecin-treated Cortical Neurons, Bioforum 6, 328-331.
Conrads, T. P., Hemann, C., George, G. N., Pickering, I. J., Prince, R. C., and Hille, R (2002) The Active Site of Arsenite Oxidase from Alcaligenes faecalis, J. Am. Chem. Soc. 124, 11276-11277.
Janini, G. M., Conrads, T. P., Veenstra, T. D., and Issaq, H. J (2003) Development of a Two Dimensional Protein/Peptide Separation Protocol for Comprehensive Proteome Measurements, J. Chrom. B 787, 43-51.
Janini, G. M., Conrads, T. P., Issaq, H. J., and Veenstra, T. D. (2003) A Rugged Sheathless CE-ESI-MS Interface for Sensitive Nanoflow Operation, Anal. Chem. 75, 1615-1619.
Tirumalai, R., Chan, K., Issaq, H. J., Conrads, T. P., and Veenstra, T. D. (2003) Characterization of the Low Molecular Weight Serum Proteome, Mol. Cell. Proteomics 2, 1096-1103.
Ory, S., Zhou, M., Conrads, T. P., Veenstra, T. D., and Morrison, D. K. (2003) PP2A Positively Regulates Ras-signaling by Dephosphorylating KSR1 and Raf-1 on Critical 14-3-3 Binding Sites, Curr. Biol. 13, 1356-1364.
Issaq, H. J., Fox, S. D., Mahadevan, M., Conrads, T. P., and Veenstra, T. D. (2003) Effect of Experimental Parameters on the HPLC Separation of Peptides and Proteins, J. Liq. Chromatogr. Relat. Technol. 26, 2255-2283.
Prieto, D., Conrads, T. P., Scudiero, N., Veenstra, T. D., and Issaq, H. J. (2003) Profiling of Secreted Proteins from Human Cancer Cell Lines by Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry, J. Liq. Chromatogr. Relat. Technol. 26, 2315-2328.
Hoang, V., Conrads, T. P., Veenstra, T. D., Blonder, J., Terunuma, A., Vogel, J. C., and Fisher, R. J. (2003) Quantitative Proteomics by Lysine Labeling, J. Biomol. Tech. 14, 216-223.
Yu, L. R., Issaq, H. J., Conrads, T. P., Uo, T., Blonder, J., Janini, G. M., Morrison, R. S., and Veenstra, T. D. (2003) Evaluation of Liquid Chromatography-Mass Spectrometry for Routine Proteome Analyses, J. Liq. Chromatogr. Relat. Technol. 26, 3331-3342.
Macpherson, G. R., Ng, S., Forbes, S. L., Melillo, G., Karpova, T., McNally, J., Conrads, T. P., Veenstra, T. D., Martinez, A., Cuttitta, F., Price, D. K., Figg, W. D. (2003) Anti-angiogenic Activity of Human Endostatin is HIF-1- independent in vitro and Sensitive to Timing of Treatment in a Human Saphenous Vein Assay, Mol. Cancer Ther. 2, 845-854.
Janini, G. M., Zhou, M., Yu, L. R., Blonder, J., Gignac, M., Conrads, T. P., Issaq, H. J., and Veenstra, T. D. (2003) On-column Sample Enrichment for Capillary Electrophoresis Sheathless Electrospray Mass Spectrometry: Evaluation for Peptide Analysis and Protein Identification, Anal. Chem. 75, 5984-5993.
Hingorani, S. R., Petricoin, E. F., Maitra, A., Rajapakse, V., Ross, S., Conrads, T. P., Veenstra, T. D., Hitt, B. A., Kawaguchi, Y., Johann, D., Liotta, L. A., Crawford, H. C., Putt, M. E., Jacks, T., Wright, C. V., Hruben, R. H., Lowy, A. M., and Tuveson, D. A. (2004) Preinvasive and Invasive Ductal Pancreatic Cancer and its Early Detection in the Mouse, Cancer Cell 4, 437-450.
Anderson, N. L., Polanski, M., Pieper, R., Gatlin, T., Tirumalai, R. S., Conrads, T. P., Veenstra, T. D., Adkins, J. A., Pounds, J. G., Lobby, A., and Richard Fagan, R. (2004) An Expanded Non-Redundant Human Plasma Proteome List Developed by Combination of Four Separate Sources, Mol. Cell. Proteomics 3, 311-326.
Xiao, Z, Conrads, T. P., Lucas, D. A., Janini, G. M., Schaefer, C. F., Buetow, K. H., Issaq, H. J., and Veenstra, T. D. (2004) Direct Ampholyte-free Liquid Phase Isoelectric Peptide Focusing: Application to the Human Serum Proteome, Electrophoresis 25, 128-133.
Blonder, J., Conrads T. P., Yu, L. R., Janini, G. M., Issaq, H. J., and Veenstra, T. D. (2004) A Detergent and Cyanogen Bromide-free Method for Integral Membrane Proteomics: Application to Halobacterium Purple Membranes, Proteomics 4, 31-45.
Berman, D. M., Shih, I. M., Burke, L. A., Veenstra, T. D., Zhou, Y. M., Conrads, T. P., Kwon, S. W., Hoang, V., Yu, L. R., Zhou, M., Kurman, K., Petricoin, E. F., and Liotta, L. A. (2004) Profiling the Activity of G Proteins in Patient-Derived Tissues by Rapid Affinity-Capture of Signal Transduction Proteins, Proteomics 4, 812-818.
Chertov, O., Biragyn, A., Kwak, L. W., Simpson, J. T., Boronina, T., Hoang, V. M., Prieto, D. A., Conrads, T. P., Veenstra, T. D., and Fisher, R. J. (2004) Organic Solvent Extraction of Proteins and Peptides from Serum as an Effective Sample Preparation for Detection and Identification of Biomarkers by Mass Spectrometry, Proteomics 4, 1195-1203.
Johnson, M. D., Yu, L-R, Conrads, T. P., Kinoshito, Y., Uo, T., Lee, S-W., Smith, R. D., Veenstra, T. D., and Morrison, R. S., (2004) Proteome Analysis of DNA Damage-Induced Neuronal Death using High Throughput Mass Spectrometry, J. Biol. Chem. 279, 26685-26697.
Blonder, J., Rodriguez, C., Lucas, D. A., Young, H., Veenstra, T. D., and Conrads, T. P. (2004) Proteomic Investigation of the Natural Killer Cell Microsomes using Gas-phase Fractionation by Mass Spectrometry, Biochim. Biophys. Acta 1698, 87-95.
Xiao, Z., Luke, B. T., Izmirlian, G., Umar, A., Lynch, P., Patterson, S., Conrads, T. P., Veenstra, T. D., Greenwald, P., Hawk, E. T., and Ali, I. U. (2004) Serum Proteomic Profiling: Search for Celecoxib-Modulated Targets and Response Predictors, Cancer Res. 64, 2904-2909.
Conrads T. P., Fusaro, V., Hitt, B. A., Chen, T. H., Wiggins, W. S., Levine, P. J., Steinberg, S. M., Kohn, E. C., Ross, S., Fishman, D. A., J. Carl Barrett, Whiteley, G., Petricoin, E. F., Liotta, L. A., and Veenstra, T. D. (2004) Use of High Resolution Serum Proteomic Patterns for Ovarian Cancer Detection, Endocr. Relat. Cancer 11, 163-178.
Chan, K. C., Lucas, D. A., Schaefer, C. F., Xiao, Z., Janini, G. M., Issaq H. J., Buetow, K. H., Veenstra, T. D., and Conrads, T. P. (2004) Analysis of the Human Serum Proteome, Clinical Proteomics 1, 101-225.
Zhou, M., Lucas, D. A., Chan, K. C., Issaq, H. J., Petricoin, E. F., Liotta, L. A., Veenstra, T. D., and Conrads, T. P. (2004) An Investigation into the Human Serum Interactome, Electrophoresis 25, 1289-1298.
Blonder, J., Hale, M. L., Lucas, D. L., Schaefer, C. F, Yu, L. R., Conrads, T. P., Issaq, H. J., Stiles, B. G. and Veenstra, T. D. (2004) Proteomic Investigation of Detergent Resistant Membrane Rafts, Electrophoresis 25, 1307-1318.
Conrads, K. A., Yu, L. R., Lucas, D. A., Chan, K. C., Issaq, H. J., Veenstra, T. D., Beck, G. R. Jr., and Conrads, T. P. (2004) Quantitative Proteomic Analysis of Inorganic Phosphate-Induced Murine MC3T3-E1 Osteoblast Cells, Electrophoresis 25, 1342-1352.
Petricoin, E. F., Rajapaske, V., Herman, E. H., Ardekani, A. M., Ross, S., Johann, D., Knapton, A., Zhang, J., Hitt, B. A., Conrads, T. P., Veenstra, T. D., Liotta, L. A., and Sistare, F.D. (2004) Toxicoproteomics: Serum Proteomic Pattern Diagnostics for Early Detection of Drug Induced Cardiac Toxicities and Cardioprotection, Toxicol. Pathol. 32, 122-130.
Yu, L. R., Conrads, T. P., Uo, T., Morrison, R. S., Chan, K., Lucas, D. A., Blonder, J., Issaq, H. J. and Veenstra, T. D. (2004) Global Analysis of the Cortical Neuron Proteome, Mol. Cell. Proteomics 3, 896-907.
Janini, G. M., Chan, K. C., Conrads, T. P., Issaq, H. J., and Veenstra, T. D. (2004) Two-dimensional Liquid Chromatography-Capillary Zone Electrophoresis Sheathless Electrospray Ionization Mass Spectrometry: Evaluation for Peptide Analysis and Protein Identification, Electrophoresis 25, 1973-1980.
Johann, D. J., McGuigan, M. D., Patel, A. R., Tomov, S., Ross, S., Conrads, T. P., Veenstra, T. D., Fishman, D. A., Whiteley, G. R., Petricoin, E. F., and Liotta, L. A. (2004) Clinical Proteomics and Biomarker Discovery, Ann. N. Y. Acad. Sci. 1022, 295-305.
Yu, L. R., Conrads, T. P., Uo, T, Issaq, H. J., Morrison, R. S., and Veenstra, T. D. (2004) An Evaluation of the New Generation of Isotope-Coded Affinity Tag Reagents: Application to Camptothecin-treated Cortical Neurons, J. Proteome Res. 3, 469-477.
Van, Q. N., Klose, J. R., Lucas, D. A., Prieto, D. A., Luke, B., Collins, J., Burt, S. K., Chmurny, G. N., Issaq, H. J., Conrads, T. P., Veenstra, T. D., and Keay, S. K. (2004) The Use of Urine Proteomic and Metabonomic Patterns for the Diagnosis of Interstitial Cystitis and Bacterial Cystitis, Dis. Markers, 19, 169-183.
Grizzle, W. E., Adam, B. L., Bigbee, W. L., Conrads, T. P., et al. (2004) Serum Protein Expression Profiling for Cancer Detection: Validation of a SELDI-Based Approach for Prostate Cancer, Dis. Markers, 19, 185-195.
Keay, S., Szekely, Z., Conrads, T. P., Veenstra, T. D., Barchi, J., Zhang, C., Koch, K., and Michjeda, C. (2004) An Antiproliferative Factor from Interstitial Cystitis Patients is a Frizzled-8 Protein-related Sialoglycopeptide, Proc. Natl. Acad. Sci. U.S.A. 101, 11803-11808.
Blonder, J., Rodriguez-Galan, M. C., Chan, K. C., Lucas, D. A, Yu, L. R., Conrads, T. P., Issaq, H. J., Young, H. A., and Veenstra, T. D. (2004) Analysis of Murine Natural Killer Cell Microsomal Proteins Using Two-Dimensional Liquid Chromatography Coupled to Tandem Electrospray Ionization Mass Spectrometry, J. Proteome Res. 3, 862-870.
Ornstein, D. K., Rayford, W., Fusaro, V. A., Conrads, T. P., Ross, SJ, Hitt, B. A., Wiggins, W. W., Veenstra, T. D., Liotta, L. A., Petricoin, E. F. (2004) Serum Proteomic Profiling can Discriminate Prostate Cancer from Benign Prostates in Men with Total Prostate Specific Antigen Levels Between 2.5 and 15.0 ng/mL, J. Urol. 172, 1302-1305
Blonder, J., Terunuma, A., Conrads, T. P., Chan, K. D., Yee, C., Lucas, D. A., Schaefer, C. F., Yu, L. R., Issaq, H. J., Veenstra, T. D. and Vogel, J. C. (2004) A Proteomic Characterization of the Plasma Membrane of Human Epidermis by High-throughput Mass Spectrometry, J. Invest. Dermatol. 123, 691-699.
Suh, S. K., Hood, B. L., Kim, B. J., Conrads, T. P., Veenstra, T. D., and Song, B. J. (2004) Identification of Oxidatively Modified Mitochondrial Proteins in Alcohol-exposed E47 HepG2 Hepatoma Cells and Mouse Liver, Proteomics 4, 3401-3412.
Karsan, A., Pollet, I., Yu, L. R., Chan, K. C., Conrads, T. P., Lucas, D. A., Andersen, R., and Veenstra, T. D. (2005) Quantitative Proteomic Analysis of Sokotrasterol Sulphate-Stimulated Primary Human Endothelial Cells, Mol. Cell. Proteomics 4, 191-204.
Liotta, L. A., Petricoin, E. F., Veenstra, T. D., and Conrads, T. P. (2004) High-resolution Serum Proteomic Patterns for Ovarian Cancer Detection, Endocr. Relat. Cancer 11, 585-587.
Saxinger, W. C., Conrads, T. P., Goldstein, D. J., and Veenstra, T. D. (2005) Fully Automated Synthesis of Phosphopeptide Arrays in Microtiter Plate Wells Provides Efficient Access to Quantitative Protein Tyrosine Kinase Characterization, BMC Immunology 6, 1-10.
Cobb, N., Conrads, T. P., and Hille, R. (2005) Mechanistic Studies of Rhodobacter sphearoides Me2SO Reductase, J. Biol. Chem. 280, 11007-11017.
Dougherty, M. K., Muller, J., Ritt, D. A., Zhou, M., Copeland, T., Conrads, T. P., Veenstra, T. D., Lu, K. P., and Morrison, D. K. (2005) Regulation of Raf-1 by Feedback Phosphorylation, Mol. Cell 17, 215-224.
Stone J. H., Rajapakse V. N., Hoffman G. S., Specks U., Merkel P. A., Spiera R., Davis J. C., St. Clair E. W., McCune J., Ross S., Hitt B. A., Veenstra T. D., Conrads T. P., Liotta L. A., and Petricoin E. F. (2005) A Serum Proteomic Approach To Gauging The State Of Remission In Wegener’s Granulomatosis, Arthritis Rheum. 52, 902-910.
Karsan, A., Blonder, J., Yaquian, E., Law, J., Lucas, D. A., Conrads, T. P., and Veenstra, T. D. (2005) Proteomic Analysis of Lipid Microdomains from Lipopolysaccharide-activated Human Endothelial Cells, J. Proteome Res. 4, 349-357.
Blonder, J., Hale, M. L., Chan, K. C., Yu, L. R., Conrads, T. P., Lucas, D. A, Zhou, M., Popoff, M. R., Issaq, H. J., Stiles, B. G., and Veenstra, T. D. (2005) Quantitative Profiling of the Detergent-Resistant Membrane Proteome of Iota b Toxin-induced Vero Cells, J. Proteome Res. 4, 523-531.
Kim, J., Yeh, D. C., Ver, M., Li, Y., Carranza, M. A., Conrads, T. P., Veenstra, T. D., Harrington, M., Quon, M. J. (2005) Phosphorylation of Ser24in the PH Domain of IRS-1 by mPLK/IRAK: Crosstalk between Inflammatory Signaling and Insulin Signaling that may Contribute to Insulin Resistance, J. Biol. Chem. 280, 23173-23183.
Brouwers, F. M., Petricoin, E. F., Ksinantova, L., Breza, J., Rajapakse, V., Ross, S., Johann, D., Mannelli, M., Shulkin, B. L., Kvetnansky, R., Eisenhofer, G., Walther, M. M., Hitt, B. A., Prieto, D. A., Hines, R. L., Conrads, T. P., Veenstra, T. D., Fusaro, V. A., Liotta, L. A., and Pacak, K. (2005) Multiple and Distint Serum Protein Patterns Distinguish Malignant from Benign Pheochromocytoma, Endocr. Relat. Cancer 12, 263-272.
Karsan, A., Eigl, B. J., Flibotte, S., Gelmon, K., Switzer, P., Hassell, P., Harrison, D., Law, J., Hayes, M., Stillwell, M., Xiao, Z., Conrads, T. P., and Veenstra, T. D. (2005) Analytical and pre-analytical biases in serum proteomic pattern analysis for breast cancer diagnosis, Clin. Chem. 51, 1525-1528.
Conrads, K. A., Yi, M., Simpson, K. A., Stevens, R., Lucas, D. A., Veenstra, T. D., Conrads, T. P., and Beck, G. R. Jr. (2005) A Combined Proteome and Microarray Investigation of Inorganic Phosphate-induced Pre-osteoblast Cells, Mol. Cell. Proteomics 4, 1284-1296.
Chertov, O., Simpson, J. T., Biragyn, A., Conrads, T. P., Veenstra, T. D., and Fisher, R. J. (2005) Enrichment of low molecular weight proteins from biofluids for biomarker discovery, Expert Rev. Proteomics 2, 139-145.
Hood, B. L., Blonder, J., Kim, G., Lucas, D. A., Chan, K. C., Issaq, H. J., Veenstra, T. D., Karsan, A., and Conrads, T. P. (2005) Quantitative analysis of the mouse low molecular weight serum proteome using 18O stable isotope labeling, J. Amer. Soc. Mass Spectrom. 16, 1221-1230.
Hood, B. L., Zhou, M., Chan, K. C., Lucas, D. A., Kim, G. J., Issaq, H. J., Veenstra, T. D., and Conrads, T. P. (2005) Investigation of the Mouse Serum Proteome, J. Proteome Res. 4, 1561-1568.
Lowenthal, M. S., Mehta, A. I., Frogale, K., Bandle, R., Araujo, R. P., Hood, B. L., Veenstra, T. D., Conrads, T. P., Goldsmith, P., Fishman, D., Petricoin III, E. F., and Liotta, L. A. (2005) Analysis of Albumin-Associated Peptides and Proteins from Ovarian Cancer Patients, Clin. Chem. 51, 1933-1945.
Imamichi, T., Conrads, T. P., Zhou, M., Liu, Y., Adelsberger, J. W., Veenstra, T. D., and Lane, H. C. (2005) A Transcription Inhibitor, Actinomycin D, Enhances HIV-1 Replication Through an Interleukin-6-Dependent Pathway, J Acquir. Immune Defic. Syndr. 40, 388-397.
Yang, G., Obiakor, H., Sinha, R. K., Newman, B. A., Hood, B. L., Conrads, T. P., Veenstra, T. D., and Mage, R. G. (2005) Activation-induced deaminase (AID): Cloning, localization, and protein extraction from young VH-mutant rabbit appendix, Proc. Natl. Acad. Sci. U.S.A. 102, 17083-17088.
Gillette, W. K., Esposito, D., Frank, P. H., Zhou, M., Yu, L. R., Jozwik, C., Zhang, X., McGowan, B., Jacobowitz, D. M., Pollard, H. B., Hao, T., Hill, D. E., Vidal, M., Conrads, T. P., Veenstra, T. D., and Hartley, J. L. (2005) POET: Using Proteomics to Screen Pools of Open Reading Frames for Protein Expression, Mol. Cell. Proteomics 4, 1647-1652.
Hood, B. L, Darfler, M. M., Guil, T. G., Furusato, B., Lucas, D. A., Ringeisen, B. R., Sesterhenn, I. A., Conrads, T. P., Veenstra, T. D., and Krizman, D. (2005) Proteomic Analysis of Formalin Fixed Prostate Cancer Tissue, Mol. Cell. Proteomics 4, 1741-1753.
Ressom, H. W., Varghese, R. S., Abdel-Hamid, M., Eissa, S., Saha, D., Goldman, L., Petricoin, E. F., Conrads, T. P., Veenstra, T. D., Loffredo, C. A., and Goldman, R. (2005) Analysis of mass spectral serum profiles for biomarker selection, Bioinformatics 21, 4039-4045.
Kong, L., Saavedra, J. E., Buzard, G. S., Xu, X., Hood, B. L., Conrads, T. P., Veenstra, T. D., and Keefer, L. K. (2006) Deamidation of peptides in aerobic nitric oxide solution by a nitrosative pathway, Nitric Oxide: Biology and Chemistry 14, 144-151.
Ali, I. U., Xiao, Z., Malone, W., Smith, M., Conrads, T. P., Veenstra, T. D., Greenwald, P., Luke, B. T. and McLarty, J. W. (2006) Plasma Proteomic Profiling: Search for Lung Cancer Diagnostic and Early Detection Markers, Oncol. Report 15, 1367-1372.
FLINT, MELANIE
Flint MS, Baum A, Chambers WH, Jenkins FJ (2007). Induction of DNA damage, alteration of DNA repair and transcriptional activation by stress hormones. Psychoneuroendocrinology. 32(5):470-9.
Yang T, MS Flint, K Webb, and Chambers WH (2006). CD161:ClrB interactions mediate activation of enhanced lysis of tumor target cells following NK cell:DC co-culture. Immunol Res. 36 (1-3): 43-50
Flint MS, Carroll JE, Jenkins FJ, Chambers WH, Han ML, Baum AS (2005). Genomic profiling of restraint stress induced alterations in mouse T lymphocytes. J. Neuroimmunology 167 (1-2): 34-44.
Flint MS, Depree K, Rich BA, Tinkle SS (2003). Differential regulation of sensitizer-induced inflammation and immunity by acute restraint stress in allergic contact dermatitis. J. Neuroimmunology 140: 28-40.
Tinkle SS, Weston AS, Flint MS (2003). Genetic factors modulate the risk of developing beryllium disease. Seminars in respiratory and critical care medicine, genetics of pulmonary disorders 24 (2): 169-177.
Flint MS, Salmen RD, Brumbaugh K, Tinkle SS (2003). Acute stress modulates the irritant component of sensitizers in allergic contact dermatitis: implications for exposure assessment. TAAP 188: 50-58.
Flint MS, Morgan JB, Shreve SN, Tinkle SS (2003). Restraint stress and corticotrophin releasing hormone modulation of murine cutaneous POMC mRNA. Stress 6: 59-62.
Flint MS and Tinkle SS (2001). C57BL/6 mice are resistant to acute restraint modulation of cutaneous hypersensitivity. Toxicological Science 62: 250-256.
Flint MS, Valosen JM, Johnson EA, Miller DB, Tinkle SS (2001). Restraint stress applied prior to chemical sensitization modulates the development of allergic contact dermatitis differently than restraint prior to challenge. J. Neuroimmunology 113: 72-80.
Tinkle SS and Flint MS (2001). Modulation of the dermal immune response by acute restraint. Toxicology of skin, 293-305 Maibach HI, editor.
Kermani F, Flint MS, Hotchkiss SAM (2000). Kinetics of induction and in situ localization of cutaneous IL-1b during the induction phase of contact sensitization. TAAP 169: 231-237.
Flint MS, Miller DB, Tinkle SS (2000). Restraint-induced modulation of allergic and irritant contact dermatitis. Brain, Behavior and Immunity 14: 256-269.
Flint MS, Dearman RJ, Kimber I, Hotchkiss SAM (1998). Production and localization of cutaneous tumour necrosis factor-a (TNF-a) and interleukin-6 (IL-6) protein and mRNA following skin sensitization of mice. Cytokine 10: 213-219.
SUTTON, JENNIFER
Sutton, J.N.;Richmond, T.; Shi, X.; Athanas, M.; Ptak, A.; Gerszten, R.; Bonilla, L. Performance Characteristics of an FT MS-based Workflow for Label-Free dMS Analysis of Human Plasma: Standards, Reproducibility, Targeted Feature Investigation, and Application to a Model of Controlled Myocardial Infarction. Submitted, Proteomics-Clinical Applications
Powell, M.J.; Sutton, J.N.; Del Castillo, C.E.; Timperman, A.T. Marine proteomics: generation of sequence tags for dissolved proteins in seawater using tandem mass spectrometry. Marine Chemistry; 2005, June, 95(3-4): 183-198
Morris, D. L., Jr.; Sutton, J. N.; Harper, R. G.; Timperman, A. T. Reversed-Phase HPLC Separation of Human Serum Employing a Novel Saw-Tooth Gradient: Toward Multidimensional Proteome Analysis, J. Proteome Res.; 2004, Nov-Dec;3(6):1149-54.
Hogan, K.T., Sutton, J.N., Chu, K.U., Busby, J.A., Shabanowitz, J., Hunt D.F., Slingluff, C.L. Jr. Use of selected reaction monitoring mass spectrometry for the detection of specific MHC class I peptide antigens on A3 supertype family members. Cancer Immunol. Immunother. 2004 Sep 16.
Harper, R. G., Workman, S.R., Timperman, A., Schuetzner, S., Sutton, JN. Low Molecular Weight Human Serum Proteome Using Ultrafiltration, Isoelectric Focusing and Mass Spectrometry. Electrophoresis, 2004, May; 25(9):1299-306.
Seamons, A. Sutton, J. Bai, D., Emily, B., Nena, B., Kafsack, B., Shabanowitz, J., Hunt, D.F., Beeson, G., Goverman, J. Competition between two MHC binding registers in a single peptide processed from myelin basic protein influences tolerance and susceptibility to autoimmunity. J Exp Med. 2003 May 19;197(10):1391-7.
Carson J., Behnam, M., Sutton, J.N, Du, C. , Wang, X., Shabanowitz, J., Hunt, D.F, Weber, M.J., and Kulik, G. Smac is required for cytochrome c-induced apoptosis in prostate epithelial cells. Cancer Res. 2002 Jan 1;62(1):18-23.
STEWART, NICOLAS
Stewart T, Stewart N. Breast cancer in female flight attendants. Lancet 1995; Nov 25;346(8987):1379.
Stewart NA, Taralp A and Kaplan H. Imprinting of lyophilized alpha-chymotrypsin affects the reactivity of the active-site imidazole. Biochem Biophys Res Commun. 1997 Nov 7;240(1):27-31.
Stewart NA, Pham VT, Choma CT and Kaplan H. Improved peptide detection with matrix-assisted laser desorption/ionization mass spectrometry by trimethylation of amino groups. Rapid Commun Mass Spectrom. 2002;16(15):1448-53.
Steeves CL, Hammer MA, Walker GB, Rae D, Stewart NA, Baltz JM. The glycine neurotransmitter transporter GLYT1 is an organic osmolyte transporter regulating cell volume in cleavage-stage embryos. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13982-7.
Basak S, Stewart NA, Chrétien M and Basak A. Aminoethyl benzenesulfonyl fluoride and its hexapeptide (Ac-VFRSLK) conjugate are both in vitro inhibitors of subtilisin kexin isozyme-1. FEBS Lett. 2004 Aug 27;573(1-3):186-94.
Stewart NA, Prieto, DA, Cosentino LM, Issaq, HJ and Veenstra TD. The approach and design of a surrogate protease substrate for disease biomarker discovery. Cell Preserv Technol., 2007 In press
